Description
SIGLEC9, also known as sialic acid-binding Ig-like lectin 9 isoform 1, is a novel member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF) expressed broadly on human blood leukocytes. It has a high-level expression in bone marrow, placenta, spleen, and fetal liver. It is a member of the recently characterized CD33-related Siglec family of sialic acid binding protein and is expressed on human monocytes and NK cells. Recombinant human SIGLEC9, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques